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/References
1. Ford AC, Marwaha A, Sood R, Moayyedi P.
Global prevalence of, and risk factors for,
uninvestigated dyspepsia: a meta-analysis. Gut
2015; 64 (7): 104957. DOI:
10.1136/gutjnl-2014-307843
2. Kim SE, Kim N, Lee JY et al. Prevalence and
Risk Factors of Functional Dyspepsia in Health
Check-up Population: A Nationwide Multicenter
Prospective Study. J Neurogastroenterol Motil
2018; 24 (4): 60313. DOI: 10.5056/jnm18068
3. Aziz I, Palsson OS, Tornblom H et al.
Epidemiology, clinical characteristics, and
associations for symptom-based Rome IV
functional dyspepsia in adults in the USA,
Canada, and the UK: a cross-sectional
population-based study. Lancet Gastroenterol
Hepatol 2018; 3 (4): 25262. DOI:
10.1016/S2468-1253(18)30003-7
4. Eusebi LH, Ratnakumaran R, Bazzoli F, Ford
AC. Prevalence of Dyspepsia in Individuals
With Gastroesophageal Reflux-Type Symptoms in
the Community: A Systematic Review and
Meta-analysis. Clin Gastroenterol Hepatol
2018; 16 (1): 3948.e1. DOI:
10.1016/j.cgh.2017.07.041
5. Sperber AD, Dumitrascu D, Fukudo S et al.
The global prevalence of IBS in adults remains
elusive due to the heterogeneity of studies: a
Rome Foundation working team literature review.
Gut 2017; 66 (6): 107582. DOI:
10.1136/gutjnl-2015-311240
6. Chatila R, Merhi M, Hariri E et al.
Irritable bowel syndrome: prevalence, risk
factors in an adult Lebanese population. BMC
Gastroenterol 2017; 17 (1): 137. DOI:
10.1186/s12876-017-0698-2
7. Althaus A, Broicher W, Wittkamp P et al.
Determinants and frequency of irritable bowel
syndrome in a German sample. Z Gastroenterol
2016; 54 (3): 21725. DOI:
10.1055/s-0041-106856
8. Yamamoto R, Kaneita Y, Osaki Y et al.
Irritable bowel syndrome among Japanese
adolescents: A nationally representative
survey. J Gastroenterol Hepatol 2015; 30 (9):
135460. DOI: 10.1111/jgh.12974
9. Klem F, Wadhwa A, Prokop LJ et al.
Prevalence, Risk Factors, and Outcomes of
Irritable Bowel Syndrome After Infectious
Enteritis: A Systematic Review and
Meta-analysis. Gastroenterology 2017; 152 (5):
104254.e1. DOI: 10.1053/j.gastro.2016.12.039
10. De Bortoli N, Frazzoni L, Savarino EV et
al. Functional Heartburn Overlaps With
Irritable Bowel Syndrome More Often than GERD.
Am J Gastroenterol 2016; 111 (12): 17117. DOI:
10.1038/ajg.2016.432
11. Paudel MS, Mandal AK, Shrestha B et al.
Prevalence of Organic Colonic Lesions by
Colonoscopy in Patients Fulfilling ROME IV
Criteria of Irritable Bowel Syndrome. JNMA J
Nepal Med Assoc 2018; 56 (209): 48792.
12. Drossman DA, Hasler WL et al. Rome-IV
Functional GI disorders: disorders of
gut-brain interaction. Gastroenterology 2016;
150 (6): 1257492.
13. Von Wulffen M, Talley NJ, Hammer J et al.
Overlap of Irritable Bowel Syndrome and
Functional Dyspepsia in the Clinical Setting:
Prevalence and Risk Factors. Dig Dis Sci 2018.
DOI: 10.1007/s10620-018-5343-6
14. de Bortoli N, Tolone S, Frazzoni M et al.
Gastroesophageal reflux disease, functional
dyspepsia and irritable bowel syndrome: common
overlapping gastrointestinal disorders. Ann
Gastroenterol 2018; 31 (6): 63948. DOI:
10.20524/aog.2018.0314
15. Ford AC, Marwaha A, Lim A, Moayyedi P.
Systematic review and meta-analysis of the
prevalence of irritable bowel syndrome in
individuals with dyspepsia. Clin Gastroenterol
Hepatol 2010; 8 (5): 4019. DOI:
10.1016/j.cgh.2009.07.020
16. Rasmussen S, Jensen TH, Henriksen SL et al.
Overlap of symptoms of gastroesophageal reflux
disease, dyspepsia and irritable bowel
syndrome in the general population. Scand J
Gastroenterol 2015; 50 (2): 1629. DOI:
10.3109/00365521.2014.983157
17. Kaji M, Fujiwara Y, Shiba M et al.
Prevalence of overlaps between GERD, FD and
IBS and impact on health-related quality of
life. J Gastroenterol Hepatol 2010; 25 (6):
11516. DOI: 10.1111/j.1440-1746.2010.06249.x
18. Shetty AJ, Balaraju G, Shetty S, Pai CG.
Quality of life in dyspepsia and its subgroups
using EQ-5D (EuroQol) questionnaire. Saudi J
Gastroenterol 2017; 23 (2): 1126. DOI:
10.4103/sjg.SJG_487_16
19. Li Y, Gong Y, Li Y et al. Sleep
disturbance and psychological distress are
associated with functional dyspepsia based on
Rome III criteria. BMC Psychiatry 2018; 18
(1): 133. DOI: 10.1186/s12888-018-1720-0
20. Matsuzaki J, Suzuki H, Togawa K et al.
Burden of impaired sleep quality on work
productivity in functional dyspepsia. United
European Gastroenterol J 2018; 6 (3): 398406.
DOI: 10.1177/2050640617726466
21. Kim SY, Choung RS, Lee SK et al.
Self-reported Sleep Impairment in Functional
Dyspepsia and Irritable Bowel Syndrome. J
Neurogastroenterol Motil 2018; 24 (2): 2808.
DOI: 10.5056/jnm17098
22. Hantoro IF, Syam AF. Measurement of
Health-Related Quality of Life in Patients
with Functional Dyspepsia. Acta Med Indones
2018; 50 (1): 8892.
23. Frandemark A, Tornblom H, Jakobsson S,
Simren M. Work Productivity and Activity
Impairment in Irritable Bowel Syndrome (IBS):
A Multifaceted Problem. Am J Gastroenterol
2018; 113 (10): 15409. DOI:
10.1038/s41395-018-0262-x
24. Hollister EB, Cain KC, Shulman RJ et al.
Relationships of Microbiome Markers With
Extraintestinal, Psychological Distress and
Gastrointestinal Symptoms, and Quality of Life
in Women With Irritable Bowel Syndrome. J Clin
Gastroenterol 2018. DOI:
10.1097/MCG.0000000000001107
25. Kopczynska M, Mokros L, Pietras T,
Malecka-Panas E. Quality of life and
depression in patients with irritable bowel
syndrome. Prz Gastroenterol 2018; 13 (2):
1028. DOI: 10.5114/pg.2018.75819
26. Aziz I, Tornblom H, Palsson OS et al. How
the Change in IBS Criteria From Rome III to
Rome IV Impacts on Clinical Characteristics
and Key Pathophysiological Factors. Am J
Gastroenterol 2018; 113 (7): 101725. DOI:
10.1038/s41395-018-0074-z
27. Hulme K, Chilcot J, Smith MA.
Doctor-patient relationship and quality of
life in Irritable Bowel Syndrome: an
exploratory study of the potential mediating
role of illness perceptions and acceptance.
Psychol Health Med 2018; 23 (6): 67484. DOI:
10.1080/13548506.2017.1417613
28. Lee SW, Chang CS, Lien HC et al. Impact of
Overlapping Functional Gastrointestinal
Disorders on the Presentation and Quality of
Life of Patients with Erosive Esophagitis and
Nonerosive Reflux Disease. Med Princ Pract
2015; 24 (5): 4915. DOI: 10.1159/000431370
29. Yi ZH, Yang ZB, Kang L et al. Clinical
features, quality of life and psychological
health of patients with irritable bowel
syndrome and functional dyspepsia. Sichuan Da
Xue Xue Bao Yi Xue Ban 2014; 45 (3): 4936.
30. Vu J, Kushnir V, Cassell B et al. The
impact of psychiatric and extraintestinal
comorbidity on quality of life and bowel
symptom burden in functional GI disorders.
Neurogastroenterol Motil 2014; 26 (9):
132332. DOI: 10.1111/nmo.12396
31. Van Oudenhove L, Crowell MD, Drossman DA
et al. Biopsychosocial Aspects of Functional
Gastrointestinal Disorders. Gastroenterology
2016. pii: S0016-5085(16)00218-3. DOI:
10.1053/j.gastro.2016.02.027.
32. Yamawaki H, Futagami S, Wakabayashi M et
al. Management of functional dyspepsia: state
of the art and emerging therapies. Ther Adv
Chronic Dis 2018; 9 (1): 2332. DOI:
10.1177/2040622317725479
33. Drossman DA, Tack J, Ford AC et al.
Neuromodulators for Functional
Gastrointestinal Disorders (Disorders of
Gut-Brain Interaction): A Rome Foundation
Working Team Report. Gastroenterology 2018;
154 (4): 114071.e1. DOI:
10.1053/j.gastro.2017.11.279
34. Pittayanon R, Yuan Y, Bollegala NP et al.
Prokinetics for Functional Dyspepsia: A
Systematic Review and Meta-analysis of
Randomized Control Trials. Am J Gastroenterol
2018. DOI: 10.1038/s41395-018-0258-6
35. Tomita T, Oshima T, Miwa H. New Approaches
to Diagnosis and Treatment of Functional
Dyspepsia. Curr Gastroenterol Rep 2018; 20
(12): 55. DOI: 10.1007/s11894-018-0663-4
36. Camilleri M. Implications of
Pharmacogenomics to the Management of IBS.
Clin Gastroenterol Hepatol 2018. pii:
S1542-3565(18)30458-0. DOI:
10.1016/j.cgh.2018.04.052
37. Nam Y, Min YS, Sohn UD. Recent advances in
pharmacological research on the management of
irritable bowel syndrome. Arch Pharm Res 2018;
41 (10): 95566. DOI:
10.1007/s12272-018-1068-5
38. Simren M, Tack J. New treatments and
therapeutic targets for IBS and other
functional bowel disorders. Nat Rev
Gastroenterol Hepatol 2018; 15 (10): 589605.
DOI: 10.1038/s41575-018-0034-5
39. Ford AC, Forman D, Bailey AG et al.
Fluctuation of gastrointestinal symptoms in
the community: a 10-year longitudinal
follow-up study. Aliment Pharmacol Ther 2008;
28 (8): 101320. DOI:
10.1111/j.1365-2036.2008.03813.x
40. Brujbu C, Macovei A. Clinical,
epidemiological and prophylactic aspects of
dyspepsia. Rev Med Chir Soc Med Nat Iasi 2014;
118 (1): 1416.
41. Levine ME, Koch SY, Koch KL. Lipase
Supplementation before a High-Fat Meal Reduces
Perceptions of Fullness in Healthy Subjects.
Gut Liver 2015; 9 (4): 4649. DOI:
10.5009/gnl14005
42. Marciani L, Cox EF, Pritchard SE et al.
Additive effects of gastric volumes and
macronutrient composition on the sensation of
postprandial fullness in humans. Eur J Clin
Nutr 2015; 69 (3): 3804. DOI:
10.1038/ejcn.2014.194
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