Italy have dropped flanker Sebastian Negri as one of three changes for their Guinness Six Nations match against England in Rome on Sunday.

Negri was the most effective carrier in the Azzurri's pack against France in round one but he is demoted to the bench in favour of South African-born Braam Steyn.

Negri was responsible for the 'crocodile roll' on Jack Willis in the same fixture last year and the Wasps flanker has been unable to play since because of the knee damage sustained.

Bordeaux's Federico Mori replaces Tommaso Menoncello on the right wing while tighthead prop Pietro Ceccarelli comes in for Tiziano Pasquali.

Italy are playing to avoid a 34th successive Six Nations defeat in a run that dates back to 2015.

Meanwhile, Eddie Jones has made six changes to the England side that were defeated by Scotland at Murrayfield last weekend. 

Rookie scrum-half Harry Randall will make his first Six Nations start after taking over the No 9 jersey from Ben Youngs, while winger Jack Nowell has replaced Elliot Daly in a re-jigged backline.

Jones has also shuffled his pack, with Jamie George and Will Stuart drafted into the front row, in place of Luke Cowan Dickie and Kyle Sinckler.

Alex Dombrandt has displaced Sam Simmonds at No 8, joining Maro Itoje and Tom Curry in the back-row.

With Lewis Ludlam injured, Itoje has been shifted to flanker, with Charlie Ewels starting at lock alongside Nick Isiekwe. 

Jones said: 'We've set ourselves the target of playing really well and lighting up Rome.

'We've made some changes and this is the best side to face Italy. We want to start fast and take the game to them.'