NEW ORLEANS — Once-daily orforglipron induced greater reductions in HbA1c than dapagliflozin and oral semaglutide for adults with type 2 diabetes, according to findings from the ACHIEVE-2 and ACHIEVE-3 trials.As Healio previously reported from the ACHIEVE-1 trial, orforglipron (Foundayo, Eli Lilly), a small molecule oral GLP-1, conferred greater decreases in HbA1c and body weight at 40 weeks than placebo for adults with type 2 diabetes. In new data from ACHIEVE-2 and ACHIEVE-3, researchers compared efficacy of orforglipron in the type 2 diabetes populations with the SGLT2 inhibitor
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