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СпутникиРНSpaceXРоскосмосNASADevelopment of the composition and manufacturing technology of orodispersible tablets (ODT) is becoming increasingly promising due to their applicability in pediatric and geriatric practice, including for patients with dysphagia or in the absence of water. Furthermore, the ability to ensure the absorption of the active pharmaceutical ingredient (API) through the oral mucosa, bypassing the gastrointestinal tract, opens up new opportunities for preventing the adverse effects of the acidic gastric environment and first-pass metabolism on the API. This article provides an overview of the principal methods and technologies for the production of ODT, featuring examples of the most advanced technologies, as well as the excipients employed.
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