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Febrile Infants in the Third Month of Life

Дата публикации: 01-08-2026 00:00:00

In their review of neonatal sepsis in 1970, Gotoff and Behrman urged clinicians to consider sepsis a threat beyond the immediate neonatal period and include the entire first month of life; they also noted that some institutions extended this consideration to include the second month. In 1976, McCarthy and Dolan extended the time period of concern to the third month, reporting “serious implications of high fever in infants.” By 1993, when an expert panel created recommendations for practice, the third month was entrenched with the second. However, as evidence-based guidelines were developed for the evaluation of young, febrile infants, the third month was generally not included with the first 2, as noted by the authors of the meta-analysis published in JAMA Pediatrics. Why is that?

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